Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 11/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015973 | 1.00 | ESR2 (0.51) | ESR2NR1H2HDAC1MAPK1RYR2 | |
| SCHEMBL28436001 | 0.85 | ESR2 (0.54) | ESR2NR1H2HDAC1MAPK1RYR2 | |
| SCHEMBL30657943 | 0.82 | KDM4E (0.49) | ESR2NR1H2HDAC1MAPK1RYR2 | |
| SCHEMBL26653897 | 0.82 | KDM4E (0.49) | ESR2NR1H2HDAC1MAPK1RYR2 | |
| SCHEMBL5848351 | 0.82 | RYR2 (0.62) | ESR2NR1H2MAPK1RYR2 | |
| SCHEMBL29984129 | 0.82 | RYR2 (0.48) | RYR2 | |
| SCHEMBL27080007 | 0.82 | RYR2 (0.48) | RYR2 | |
| SCHEMBL29134507 | 0.80 | RYR2 (0.51) | RYR2ABHD6 | |
| SCHEMBL29528794 | 0.80 | ESR2 (0.74) | ESR2NR1H2HDAC1MAPK1ABHD6 | |
| SCHEMBL29587073 | 0.80 | NR1H2 (0.72) | ESR2NR1H2HDAC1MAPK1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522280-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023220219-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |