Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 18/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29984129 | 0.87 | RYR2 (0.48) | RYR2HSD17B3 | |
| SCHEMBL27080007 | 0.87 | RYR2 (0.48) | RYR2HSD17B3 | |
| SCHEMBL30015973 | 0.80 | ESR2 (0.51) | RYR2ABHD6 | |
| SCHEMBL26654042 | 0.80 | ESR2 (0.51) | RYR2ABHD6 | |
| SCHEMBL3430812 | 0.79 | RYR2 (0.67) | RYR2 | |
| SCHEMBL31598007 | 0.75 | ABHD6 (0.59) | HSD17B3ABHD6 | |
| SCHEMBL3808915 | 0.75 | ABHD6 (0.59) | HSD17B3ABHD6 | |
| SCHEMBL587507 | 0.75 | ABHD6 (0.59) | HSD17B3ABHD6 | |
| SCHEMBL12313606 | 0.75 | RYR2 (0.54) | RYR2 | |
| SCHEMBL4437450 | 0.74 | ABHD6 (0.55) | HSD17B3ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |