Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331135 | 0.84 | AKR1B1 (0.41) | KDM4EALDH1A1GAA | |
| SCHEMBL4536902 | 0.67 | ALDH1A1 (0.34) | KDM4EALDH1A1CA2 | |
| SCHEMBL5026780 | 0.65 | — | — | |
| SCHEMBL7448543 | 0.62 | CA2 (0.31) | CA2 | |
| SCHEMBL10339218 | 0.61 | AKR1B1 (0.46) | KDM4EALDH1A1CA2GAANPSR1 | |
| Water SCHEMBL8690920 | 0.61 | CA2 (0.31) | CA2 | |
| Hydrochloric Acid SCHEMBL8688918 | 0.61 | CA2 (0.31) | CA2 | |
| SCHEMBL8556258 | 0.60 | MAPT (0.38) | KDM4EALDH1A1CA2GAANPSR1 | |
| Methyl Alcohol SCHEMBL8692962 | 0.60 | HTT (0.31) | — | |
| SCHEMBL30390479 | 0.60 | HTT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468559-B1 | METHODS OF USE AND PHARMACEUTICAL COMBINATIONS OF HDAC INHIBITORS WITH BET INHIBITORS | DANA FARBER CANCER INST INC (US) | 2023-11-22 | — | — | EP | claimed |