Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.60 |
| ▸ | GIPR | P48546 | 12/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665459 | 0.92 | GCGR (0.62) | GCGRGIPROPRM1OPRK1MAPT | |
| SCHEMBL2665786 | 0.90 | GCGR (0.66) | GCGRGIPROPRM1OPRK1 | |
| SCHEMBL9071759 | 0.90 | GCGR (0.57) | GCGRGIPROPRM1OPRK1STAT3 | |
| SCHEMBL2650880 | 0.89 | GCGR (0.67) | GCGRGIPROPRM1OPRK1 | |
| SCHEMBL9071304 | 0.88 | GCGR (0.55) | GCGRGIPROPRM1OPRK1STAT3 | |
| SCHEMBL2665464 | 0.87 | GCGR (0.62) | GCGRGIPRMAPT | |
| SCHEMBL9071788 | 0.86 | GCGR (0.68) | GCGRGIPRSTAT3 | |
| SCHEMBL2665594 | 0.86 | GCGR (0.69) | GCGRGIPRSTAT3 | |
| SCHEMBL9071764 | 0.85 | GCGR (0.69) | GCGRGIPR | |
| SCHEMBL9071761 | 0.84 | GCGR (0.70) | GCGRGIPRSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000612-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-01-03 | — | — | WO | disclosed |