Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.66 |
| ▸ | GIPR | P48546 | 17/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665659 | 0.92 | GCGR (0.78) | GCGRGIPRGLP1R | |
| SCHEMBL2665459 | 0.91 | GCGR (0.62) | GCGRGIPROPRM1OPRK1 | |
| SCHEMBL2665463 | 0.90 | GCGR (0.60) | GCGRGIPROPRM1OPRK1 | |
| SCHEMBL9071764 | 0.89 | GCGR (0.69) | GCGRGIPRGLP1R | |
| SCHEMBL9071788 | 0.89 | GCGR (0.68) | GCGRGIPRGLP1R | |
| SCHEMBL9071790 | 0.89 | GCGR (0.70) | GCGRGIPRGLP1R | |
| SCHEMBL9071761 | 0.89 | GCGR (0.70) | GCGRGIPRGLP1R | |
| SCHEMBL2665594 | 0.88 | GCGR (0.69) | GCGRGIPRGLP1R | |
| SCHEMBL2665795 | 0.88 | GCGR (0.69) | GCGRGIPRGLP1R | |
| SCHEMBL9071840 | 0.88 | GCGR (0.84) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000612-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-01-03 | — | — | WO | disclosed |