Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18889781 | 0.82 | LDHA (0.62) | COMTPSIP1LDHAAPEX1CA1 | |
| SCHEMBL15461558 | 0.82 | RXFP1 (0.50) | RXFP1MAPK10NPSR1FABP4MEN1 | |
| SCHEMBL15514563 | 0.79 | LDHA (0.64) | RXFP1MAPK10NPSR1FABP4MEN1 | |
| SCHEMBL30987398 | 0.78 | RXFP1 (0.46) | RXFP1MAPK10NPSR1FABP4MEN1 | |
| SCHEMBL3578778 | 0.78 | FABP4 (0.51) | RXFP1MAPK10NPSR1FABP4MEN1 | |
| SCHEMBL2385214 | 0.78 | RXFP1 (0.46) | RXFP1MAPK10NPSR1FABP4MEN1 | |
| SCHEMBL16467685 | 0.77 | RXFP1 (0.47) | RXFP1MAPK10NPSR1FABP4MEN1 | |
| SCHEMBL31378576 | 0.77 | PLCG1 (0.72) | MEN1KMT2APLCG1PSIP1L3MBTL1 | |
| SCHEMBL1814352 | 0.77 | PLCG1 (0.72) | MEN1KMT2APLCG1PSIP1L3MBTL1 | |
| SCHEMBL6614757 | 0.76 | FABP4 (0.50) | RXFP1MAPK10NPSR1FABP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524139-A1 | IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-117069725-A | Imidazopyridazine substituted benzene ring derivative, preparation method, pharmaceutical composition and application | 上海赛默罗生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023216753-A1 | IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 上海赛默罗生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |