Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 4/20 | 0.54 |
| ▸ | NPY1R | P25929 | 3/20 | 0.54 |
| ▸ | NPY2R | P49146 | 3/20 | 0.54 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30252225 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL29948864 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL266555 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL4293347 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL29365741 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL4293356 | 1.00 | NPY4R (0.54) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL4420809 | 0.98 | ENPEP (0.56) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL5032917 | 0.97 | ENPEP (0.56) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL31467474 | 0.97 | ERAP2 (0.55) | NPY4RNPY1RNPY2RENPEPERAP2 | |
| SCHEMBL27906634 | 0.94 | ENPEP (0.52) | NPY4RNPY1RNPY2RENPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103111093-B | The preparation of flag peptide tag recombinant protein immunoaffinity purification enriching column and application thereof | NANJING LANGUANG (BLUE LIGHT) BIOTECHNOLOGY INC. (CN) | 2015-07-29 | — | — | CN | claimed |
| CN-103111093-A | Preparation and application of flag peptide tagged recombinant protein immunoaffinity purification and enrichment column | NANNING LANGUANG BLUE LIGHT BIOTECHNOLOGY INC | 2013-05-22 | — | — | CN | claimed |
| US-20190270787-A1 | CYSTEINE VARIANTS OF INTERLEUKIN-11 AND METHODS OF USE THEREOF | BOLDER BIOTECHNOLOGY, INC. | 2019-09-05 | — | — | US | disclosed |
| US-10329337-B2 | Method to increase the number of circulating platelets by administering PEGylated cysteine variants of IL-11 | BOLDER BIOTECHNOLOGY, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-20170369547-A1 | CYSTEINE VARIANTS OF INTERLEUKIN-11 AND METHODS OF USE THEREOF | BOLDER BIOTECHNOLOGY, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9637530-B2 | Methods of preparing cysteine variants of human recombinant IL-11 | BOLDER BIOTECHNOLOGY, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-20160200790-A1 | CYSTEINE VARIANTS OF INTERLEUKIN-11 AND METHODS OF USE THEREOF | BOLDER BIOTECHNOLOGY, INC. (US) | 2016-07-14 | — | — | US | disclosed |
| CN-103111093-B | The preparation of flag peptide tag recombinant protein immunoaffinity purification enriching column and application thereof | NANJING LANGUANG (BLUE LIGHT) BIOTECHNOLOGY INC. (CN) | 2015-07-29 | — | — | CN | disclosed |
| US-8957023-B2 | Methods for making proteins containing free cysteine residues | BOLDER BIOTECHNOLOGY INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8748392-B2 | Methods of treatment using cysteine variants of interleukin-11 | BOLDER BIOTECHNOLOGY INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20130217629-A1 | METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES | BOLDER BIOTECHNOLOGY, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| CN-1210400-C | Methods for making proteins containing free cysteine residues | BOLDER BIOTECHNOLOGY INC (US) | 2005-07-13 | — | — | CN | disclosed |
| EP-1379266-A4 | MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS | SURROMED INC (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20040086515-A1 | Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease | SURROMED, INC. (US) | 2004-05-06 | — | — | US | disclosed |
| WO-2004013303-A2 | MODIFIED ANNEXIN PROTEINS AND METHODS FOR TREATING VASO-OCCLUSIVE SICKLE-CELL DISEASE | SURROMED, INC. (US) | 2004-02-12 | — | — | WO | disclosed |
| EP-1379266-A2 | MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS | SurroMed, Inc. (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20030166532-A1 | Modified annexin proteins and methods for preventing thrombosis | SURROMED, INC. | 2003-09-04 | — | — | US | disclosed |
| WO-2002067857-A3 | MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS | SURROMED INC (US) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002067857-A2 | MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS | SURROMED, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| CN-1355842-A | Methods for making proteins containing free cysteine residues | BOLDER BIOTECHNOLOGY INC (US) | 2002-06-26 | — | — | CN | disclosed |