SCHEMBL266555

SCHEMBL266555

NCCCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 4/20 0.54
NPY1R P25929 3/20 0.54
NPY2R P49146 3/20 0.54
ENPEP Q07075 5/20 0.53
ERAP2 Q6P179 1/20 0.52
LNPEP Q9UIQ6 1/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.49
NPY5R Q15761 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL266554 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL30252225 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL29948864 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL4293347 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL29365741 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL4293356 1.00 NPY4R (0.54) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL4420809 0.98 ENPEP (0.56) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL5032917 0.97 ENPEP (0.56) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL31467474 0.97 ERAP2 (0.55) NPY4RNPY1RNPY2RENPEPERAP2
SCHEMBL27906634 0.94 ENPEP (0.52) NPY4RNPY1RNPY2RENPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282878-A1 COMPOSITIONS AND METHODS FOR MODULATING ANTIGEN BINDING ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-09-11 US claimed
CN-119301105-A Thiostrepton-based compounds for the treatment of cancer and preparation thereof RS肿瘤学有限责任公司 2025-01-10 CN claimed
WO-2023212662-A2 COMPOSITIONS AND METHODS FOR MODULATING ANTIGEN BINDING ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-11-02 WO claimed
US-11649267-B2 Mitrecin A polypeptide with antimicrobial activity THE MITRE CORPORATION (US) 2023-05-16 US claimed
CN-103111093-B The preparation of flag peptide tag recombinant protein immunoaffinity purification enriching column and application thereof NANJING LANGUANG (BLUE LIGHT) BIOTECHNOLOGY INC. (CN) 2015-07-29 CN claimed
CN-103111093-A Preparation and application of flag peptide tagged recombinant protein immunoaffinity purification and enrichment column NANNING LANGUANG BLUE LIGHT BIOTECHNOLOGY INC 2013-05-22 CN claimed
EP-4749281-A2 DETECTOR UK NIVD Ltd (GB) 2026-05-27 EP disclosed
US-20260125474-A1 Anti-CTLA-4 Binding Proteins and Methods of Use Thereof GIGAGEN INC (US) 2026-05-07 US disclosed
EP-3985024-B1 ANTI-ACTIVIN-A ANTIBODY AND CHEMOTHERAPY COMBINATION FOR THE TREATMENT OF OVARIAN CANCER ATARA BIOTHERAPEUTICS INC (US) 2026-05-06 EP disclosed
US-12595501-B2 Expression of products from nucleic acid concatemers GLOBAL LIFE SCIENCES SOLUTIONS USA LLC (US) 2026-04-07 US disclosed
US-12589139-B2 Clostridial neurotoxins comprising an exogenous activation loop IPSEN BIOPHARM LIMITED (GB) 2026-03-31 US disclosed
US-20260049985-A1 Localized Surface Plasmon Resonance Detector UK NIVD LTD (GB) 2026-02-19 US disclosed
US-12545728-B2 Treatment of cancer metastasis by targeting exosome proteins LONZA SALES AG (CH) 2026-02-10 US disclosed
EP-1379266-A4 MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS SURROMED INC (US) 2004-05-06 EP disclosed
WO-2004013303-A2 MODIFIED ANNEXIN PROTEINS AND METHODS FOR TREATING VASO-OCCLUSIVE SICKLE-CELL DISEASE SURROMED, INC. (US) 2004-02-12 WO disclosed
EP-1379266-A2 MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS SurroMed, Inc. (US) 2004-01-14 EP disclosed
US-20030166532-A1 Modified annexin proteins and methods for preventing thrombosis SURROMED, INC. 2003-09-04 US disclosed
WO-2002067857-A3 MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS SURROMED INC (US) 2002-11-07 WO disclosed
WO-2002067857-A2 MODIFIED ANNEXIN PROTEINS AND METHODS FOR PREVENTING THROMBOSIS SURROMED, INC. (US) 2002-09-06 WO disclosed
CN-1355842-A Methods for making proteins containing free cysteine residues BOLDER BIOTECHNOLOGY INC (US) 2002-06-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589139-B2 Clostridial neurotoxins comprising an exogenous activation loop PDXK, VIP, F13B NPY4R 133/4885NPY1R 26/4885NPY2R 115/4885
US-20260125474-A1 Anti-CTLA-4 Binding Proteins and Methods of Use Thereof CD274, MICA, PDCD1LG2 NPY4R 294/4885NPY1R 315/4885NPY2R 792/4885
US-12545728-B2 Treatment of cancer metastasis by targeting exosome proteins ENPP3, ENTPD3, ENTPD2 NPY4R 3019/4885NPY1R 3401/4885NPY2R 3197/4885
US-20260049985-A1 Localized Surface Plasmon Resonance Detector SHBG, FCGR3B, LGALS3BP NPY4R 352/4885NPY1R 226/4885NPY2R 542/4885
US-12595501-B2 Expression of products from nucleic acid concatemers SRRT, TELO2, INCENP NPY4R 1621/4885NPY1R 667/4885NPY2R 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.