Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454882 | 0.85 | PYCR1 (0.45) | MAPK1HTTTDP1CYP1A2CYP2D6 | |
| SCHEMBL29278120 | 0.78 | MPO (0.38) | KDM4EMEN1MAPK1KMT2AMAPT | |
| SCHEMBL30762191 | 0.78 | MPO (0.38) | KDM4EMEN1MAPK1KMT2AMAPT | |
| SCHEMBL11453476 | 0.77 | HRH3 (0.48) | MAPTKCNH2 | |
| SCHEMBL26658411 | 0.76 | TSHR (0.41) | KDM4ELMNAMAPTPOLBTSHR | |
| SCHEMBL31500392 | 0.75 | TSHR (0.53) | KDM4ERECQLTSHRCYP3A4 | |
| SCHEMBL11466186 | 0.75 | TSHR (0.53) | KDM4ERECQLTSHRCYP3A4 | |
| SCHEMBL11461540 | 0.75 | BCHE (0.53) | LMNAMAPTALDH1A1TSHRCYP1A2 | |
| SCHEMBL26658413 | 0.74 | PDGFRB (0.34) | KDM4EMEN1MAPK1KMT2AMAPT | |
| SCHEMBL2014012 | 0.73 | PRKCI (0.67) | KDM4EMEN1MAPK1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023203254-A2 | EFFECTIVE MEANS TO MODULATE NMDA RECEPTOR-MEDIATED TOXICITY | FUNDAMENTAL PHARMA GMBH (DE) | 2023-10-26 | — | — | WO | disclosed |