Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267691 | 0.80 | MAPK1 (0.42) | MAPK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26656363 | 0.79 | MAPK1 (0.34) | MAPK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26656317 | 0.78 | MAPK1 (0.36) | MAPK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26818892 | 0.70 | NOTUM (0.48) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL27179041 | 0.66 | ALDH1A1 (0.53) | ALDH1A1SLC6A2 | |
| SCHEMBL12729547 | 0.64 | ROCK1 (0.46) | MAPK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5352707 | 0.63 | NOTUM (0.35) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL11595994 | 0.61 | ALDH1A1 (0.36) | MAPK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26656347 | 0.60 | POLB (0.38) | MAPK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL12646849 | 0.59 | ALDH1A1 (0.46) | MAPK1ALDH1A1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526289-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |