Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 7/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12363786 | 0.73 | POLB (0.41) | POLBCA1CA2HTR2AHTR2C | |
| SCHEMBL18373772 | 0.71 | POLB (0.40) | POLBCA1CA2HTR2AHTR2C | |
| SCHEMBL13068270 | 0.71 | HTT (0.40) | POLBCA1CA2HTR2AHTR2C | |
| SCHEMBL26817417 | 0.70 | NOTUM (0.62) | POLBCA1CA2MAPK1NPC1 | |
| SCHEMBL14608536 | 0.69 | NOTUM (0.45) | POLBCA1CA2MAPK1NPC1 | |
| SCHEMBL13267691 | 0.68 | MAPK1 (0.42) | MAPK1GRIA2NPC1ALDH1A1HTT | |
| SCHEMBL8264212 | 0.65 | L3MBTL1 (0.35) | MAPK1ALDH1A1 | |
| SCHEMBL25290240 | 0.65 | POLB (0.41) | POLBCA1CA2MAPK1GRIA2 | |
| SCHEMBL13077984 | 0.65 | HSD11B1 (0.39) | ALDH1A1 | |
| SCHEMBL6684665 | 0.63 | PRCP (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526289-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |