Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26667268 | 0.93 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1GMNNLMNA | |
| SCHEMBL3673039 | 0.86 | RAB9A (0.73) | RAB9ASMN1; SMN2NPC1GMNNLMNA | |
| SCHEMBL26656945 | 0.85 | HTT (0.63) | HTTIDH1CPT2CPT1ACPT1B | |
| SCHEMBL26656817 | 0.85 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2NPC1IDH1CPT2 | |
| SCHEMBL26657377 | 0.84 | RXFP1 (0.66) | SMN1; SMN2LMNATHRBIDH1CPT2 | |
| SCHEMBL26657444 | 0.83 | EPAS1 (0.55) | IDH1CPT2CPT1ACPT1B | |
| SCHEMBL26657415 | 0.83 | IDH1 (0.56) | IDH1CPT2CPT1ACPT1BRXFP1 | |
| SCHEMBL26656950 | 0.83 | IDH1 (0.60) | IDH1CPT2CPT1ACPT1BRXFP1 | |
| SCHEMBL26657728 | 0.82 | CPT2 (0.64) | RAB9AHTTIDH1CPT2CPT1A | |
| SCHEMBL26657374 | 0.82 | RXFP1 (0.62) | SMN1; SMN2LMNAHTTIDH1CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339851-A1 | CXCR6 SULFONAMIDE COMPOUNDS | CHEMOCENTRYX, INC. | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339851-A1 | CXCR6 SULFONAMIDE COMPOUNDS | CXCR6, CXCR1, CXCR2 | RAB9A 1756/4885SMN1; SMN2 2414/4885NPC1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.