SCHEMBL2665768

SCHEMBL2665768

CC(F)(F)c1cc(-c2csc(N(CCc3ccccc3)Cc3ccc(C(=O)NCCC(=O)O)cc3)n2)cc(C(F)(F)F)c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.62
GIPR P48546 19/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665776 0.82 GCGR (0.67) GCGRGIPR
SCHEMBL2665971 0.82 GCGR (0.54) GCGRGIPR
SCHEMBL2665767 0.81 GCGR (0.53) GCGRGIPR
SCHEMBL9071163 0.81 GCGR (0.61) GCGRGIPR
SCHEMBL2648112 0.81 GCGR (0.75) GCGRGIPR
SCHEMBL6135592 0.81 GCGR (0.83) GCGRGIPR
SCHEMBL2665810 0.80 GCGR (0.55) GCGRGIPR
SCHEMBL9071178 0.78 GCGR (0.68) GCGRGIPR
SCHEMBL2647463 0.78 GCGR (0.88) GCGRGIPR
SCHEMBL2665992 0.78 GCGR (0.75) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed