Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.55 |
| ▸ | GIPR | P48546 | 18/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071163 | 0.87 | GCGR (0.61) | GCGRGIPR | |
| SCHEMBL2665740 | 0.84 | GCGR (0.43) | GCGRGIPR | |
| SCHEMBL18674589 | 0.81 | GCGR (0.63) | GCGRGIPR | |
| SCHEMBL2665768 | 0.80 | GCGR (0.62) | GCGRGIPR | |
| SCHEMBL2665776 | 0.80 | GCGR (0.67) | GCGRGIPR | |
| SCHEMBL2665840 | 0.79 | GCGR (0.87) | GCGRGIPR | |
| SCHEMBL9071178 | 0.79 | GCGR (0.68) | GCGRGIPR | |
| SCHEMBL2665737 | 0.79 | GCGR (0.61) | GCGRGIPR | |
| SCHEMBL2665774 | 0.78 | GCGR (0.60) | GCGRGIPR | |
| SCHEMBL9071175 | 0.78 | GCGR (0.52) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |