Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665739 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2NPSR1KMT2A | |
| SCHEMBL25376216 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2NPSR1KMT2A | |
| SCHEMBL15416895 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2NPSR1KMT2A | |
| SCHEMBL18635939 | 0.69 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2NPSR1KMT2A | |
| SCHEMBL15637983 | 0.69 | SMN1; SMN2 (0.63) | ALDH1A1KDM4ESMN1; SMN2NPSR1KMT2A | |
| SCHEMBL6072254 | 0.69 | CHRM2 (0.72) | ALDH1A1KDM4EKMT2AMEN1CHRM2 | |
| SCHEMBL8160775 | 0.69 | HIF1A (0.53) | SMN1; SMN2LMNATP53FFAR1 | |
| SCHEMBL19559071 | 0.68 | CHRM2 (0.56) | ALDH1A1KDM4EKMT2AMEN1CHRM2 | |
| Iodide SCHEMBL9478324 | 0.67 | CHRM2 (0.69) | ALDH1A1KDM4EKMT2AMEN1CHRM2 | |
| SCHEMBL24181481 | 0.67 | PTGS1 (0.39) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |