Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GCG | P01275 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071165 | 0.82 | HDAC8 (0.58) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5940285 | 0.81 | FOLH1 (0.58) | ALDH1A1KDM4ESMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL28654120 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2HIF1AKMT2AL3MBTL1 | |
| SCHEMBL2665822 | 0.78 | NPC1 (0.62) | SMN1; SMN2KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL28665708 | 0.78 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2HIF1AKMT2ANPSR1 | |
| SCHEMBL2665809 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL9072937 | 0.77 | CA1 (0.52) | L3MBTL1MAPK1HDAC8HDAC6LMNA | |
| SCHEMBL2663201 | 0.76 | GCGR (0.53) | SMN1; SMN2HIF1AKMT2AL3MBTL1GCG | |
| SCHEMBL9071169 | 0.76 | PPARG (0.47) | L3MBTL1MAPK1LMNA | |
| SCHEMBL15637983 | 0.75 | SMN1; SMN2 (0.63) | ALDH1A1KDM4ESMN1; SMN2HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |