Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665808 | 0.92 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL6569873 | 0.76 | RAB9A (0.78) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL9441440 | 0.75 | EPHX1 (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8167648 | 0.75 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL23023044 | 0.74 | EPHX1 (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31612285 | 0.73 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL3635519 | 0.72 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL9071165 | 0.72 | HDAC8 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23004911 | 0.71 | HTT (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23023189 | 0.71 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |