SCHEMBL26658359

SCHEMBL26658359

CC(C)CNC(=O)CC(CNC(=O)C(C)C)NC(=O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
HPGD P15428 5/20 0.37
MMP1 P03956 1/20 0.36
MMP8 P22894 1/20 0.36
MAPT P10636 2/20 0.35
RECQL P46063 1/20 0.35
EPHX2 P34913 2/20 0.35
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26658336 0.87 PSMB5 (0.39) CYP2D6CYP2C19HPGDSMN1; SMN2GAA
SCHEMBL26658332 0.86 MCL1 (0.33) SMN1; SMN2
SCHEMBL26659398 0.84 MMP2 (0.31) CYP2D6CYP2C19MMP8
SCHEMBL3354440 0.80 CYP2D6 (0.59) CYP2D6CYP2C19HPGDMMP1MMP8
SCHEMBL26658674 0.77
SCHEMBL25891221 0.75 CYP2D6 (0.48) CYP2D6CYP2C19HPGDMMP1MMP8
SCHEMBL26658644 0.75 CYP2C9 (0.34) LMNA
SCHEMBL6644938 0.74 CYP2D6 (0.56) CYP2D6CYP2C19HPGDMMP1MMP8
SCHEMBL26658439 0.73 MTNR1A (0.36) CYP2D6CYP2C19KDM4E
SCHEMBL5907680 0.70 CYP2D6 (0.52) CYP2D6CYP2C19HPGDMMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11802211-B2 Polymeric dyes and uses thereof BECTON, DICKINSON AND COMPANY (US) 2023-10-31 US disclosed