SCHEMBL266594

SCHEMBL266594

Cc1ccc(C)c(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019312 1.00
SCHEMBL29670201 0.78
SCHEMBL487841 0.78
SCHEMBL940010 0.78
SCHEMBL29561566 0.78
Hydrochloric Acid SCHEMBL6588208 0.76 NOS3 (0.37)
SCHEMBL24742242 0.74
SCHEMBL250736 0.74
SCHEMBL4022308 0.74
SCHEMBL21856101 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-4705298-A2 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-03-11 EP disclosed
US-12559508-B2 Semi-saturated bicyclic derivatives and related uses MOMA THERAPEUTICS, INC. (US) 2026-02-24 US disclosed
US-20250230171-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2025-07-17 US disclosed
US-20250049772-A1 PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-02-13 US disclosed
US-12195482-B1 Compounds as inhibitors of AXL ARCUS BIOSCIENCES, INC. (US) 2025-01-14 US disclosed
US-20240425526-A1 COMPOUNDS AS INHIBITORS OF AXL ARCUS BIOSCIENCES, INC. (US) 2024-12-26 US disclosed
WO-2024211836-A2 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. (US) 2024-10-10 WO disclosed
EP-4217062-B1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-10-09 EP disclosed
US-12037323-B2 Uracil derivatives as Mer-AXL inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-16 US disclosed
WO-2006065204-A1 SUBSTITUTED AMINOPYRIDINES AND USES THEREOF ASTRAZENECA AB (SE) 2006-06-22 WO disclosed
WO-2006065204-A1 SUBSTITUTED AMINOPYRIDINES AND USES THEREOF ASTRAZENECA AB (SE) 2006-06-22 WO disclosed
CN-1152021-C Corticotropin release factors antagonistic agent ������ҩ�����޹�˾ 2004-06-02 CN disclosed
CN-1082949-C Process for converting 2, 4-dichloropyridines into 2-aryloxy-4-chloropyridines PFIZER (US) 2002-04-17 CN disclosed
CN-1246475-A Corticotropin release factors antagonistic agent PFIZER (US) 2000-03-08 CN disclosed
CN-1049659-C Corticotropin releasing factor antagonists PFIZER (US) 2000-02-23 CN disclosed
CN-1186486-A Process for converting 2, 4-dichloropyridines into 2-aryloxy-4-chloropyridines PFIZER (US) 1998-07-01 CN disclosed
CN-1150428-A Corticotropin releasing factor antagonists PFIZER (US) 1997-05-21 CN disclosed
US-4898608-A Pyridylthio-acylanilide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-02-06 US disclosed
EP-0243868-A2 Pyridylthio-acylanilides BAYER AG (DE) 1987-11-04 EP disclosed