Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 4/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.32 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049656 | 0.76 | NOS2 (0.40) | BACE1NOS2NOS3NOS1 | |
| SCHEMBL18314661 | 0.76 | BACE1 (0.50) | BACE1KMT2AKDM4EALDH1A1AR | |
| SCHEMBL18369638 | 0.73 | BACE1 (0.47) | BACE1KMT2AKDM4EALDH1A1AR | |
| SCHEMBL31256111 | 0.73 | NOS2 (0.34) | KDM4ENOS2NOS3NOS1 | |
| SCHEMBL3385612 | 0.72 | BACE1 (0.35) | BACE1ALDH1A1ARRAB9A | |
| SCHEMBL3385616 | 0.72 | BACE1 (0.35) | BACE1ALDH1A1ARRAB9A | |
| SCHEMBL18310643 | 0.71 | BACE1 (0.46) | BACE1KMT2AKDM4EALDH1A1AR | |
| SCHEMBL18368421 | 0.70 | BACE1 (0.45) | BACE1KMT2AKDM4EALDH1A1AR | |
| SCHEMBL18368422 | 0.69 | KDM4E (0.45) | BACE1KMT2AKDM4EALDH1A1AR | |
| SCHEMBL9289684 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1HSP90AA1HSP90AB1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217095-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SYNRX THERAPEUTICS (HANGZHOU) CO., LTD. (CN) | 2023-11-16 | — | — | WO | disclosed |