SCHEMBL266609

SCHEMBL266609

Cc1ccc2nc(C)[nH]c2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.66
KMT2A Q03164 3/20 0.61
POLB P06746 2/20 0.61
USP2 O75604 1/20 0.59
HPGD P15428 1/20 0.59
HTT P42858 1/20 0.59
CYP1A2 P05177 1/20 0.58
HSP90AA1 P07900 1/20 0.58
ESR2 Q92731 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
PIN1 Q13526 1/20 0.58
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
GAA P10253 2/20 0.56
HSD17B10 Q99714 2/20 0.56
MAPT P10636 2/20 0.56
KDM4E B2RXH2 2/20 0.53
PKM P14618 1/20 0.53
ADORA2A P29274 1/20 0.53
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29727934 1.00 ALDH1A1 (0.66) ALDH1A1KMT2APOLBUSP2HPGD
SCHEMBL15477598 0.92 ALDH1A1 (0.58) ALDH1A1KMT2APOLBUSP2HPGD
SCHEMBL14665476 0.86 NPC1 (0.75) ALDH1A1KMT2APOLBUSP2HPGD
SCHEMBL13120680 0.85 NPC1 (0.68) ALDH1A1KMT2APOLBUSP2HPGD
SCHEMBL30572488 0.84 RAB9A (0.59) ALDH1A1KMT2APOLBHPGDHTT
SCHEMBL15747134 0.84 RAB9A (0.59) ALDH1A1KMT2APOLBHPGDHTT
SCHEMBL9980119 0.84 RAB9A (0.59) ALDH1A1KMT2APOLBHPGDHTT
SCHEMBL12540 0.83 ALDH1A1 (0.50) ALDH1A1KMT2APOLBUSP2HPGD
SCHEMBL2457137 0.83 RAB9A (0.67) ALDH1A1KMT2APOLBHPGDHSP90AA1
Benzimidazole SCHEMBL7506137 0.81 RAB9A (0.52) ALDH1A1KMT2APOLBUSP2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 875 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163322-A1 ETCHING COMPOSITION AND METHOD FOR PRODUCING WIRING BOARD USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-22 US claimed
US-9486892-B2 Polishing composition FUJIMI INCORPORATED (JP) 2016-11-08 US claimed
US-20250263760-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-08-21 US disclosed
US-12319946-B2 Methods for producing modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-06-03 US disclosed
US-20250163322-A1 ETCHING COMPOSITION AND METHOD FOR PRODUCING WIRING BOARD USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-22 US disclosed
US-20240400401-A1 USE OF CATIONS SELECTED FROM 1,2,3,5-TETRAMETHYL-BENZIMIDAZOLIUM, 1,2,3,4,5-PENTAMETHYLBENZIMIDAZOLIUM, AND 1,2,3,4,6-PENTAMETHYLBENZIMIDAZOLIUM AS STRUCTURE DIRECTING AGENTS FOR THE PREPARATION OF MOLECULAR SIEVES AND MOLECULAR SIEVES OBTAINED USING THE SAME ExxonMobil Technology and Engineering Company 2024-12-05 US disclosed
US-20240229090-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240229090-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240229090-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
WO-2024126987-A1 INHIBITORY COMPOUNDS STORM THERAPEUTICS LIMITED (GB) 2024-06-20 WO disclosed
US-11992914-B2 Polishing composition, polishing method, and method for producing substrate FUJIMI INCORPORATED (JP) 2024-05-28 US disclosed
WO-2004067529-A1 INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS ELI LILLY AND COMPANY (US) 2004-08-12 WO disclosed
EP-0734386-B1 PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES ABBOTT LAB (US) 2002-02-06 EP disclosed
US-6252084-B1 THERAPY FOR SEPSIS SHOCK ELI LILLY AND COMPANY 2001-06-26 US disclosed
EP-0620215-B1 1H-indole-3-acetamide derivatives as sPLA2 inhibitors LILLY CO ELI (US) 1999-08-18 EP disclosed
US-5684034-A INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE ELI LILLY AND COMPANY (US) 1997-11-04 US disclosed
EP-0734386-A1 PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES Abbott Laboratories (US) 1996-10-02 EP disclosed
US-5486525-A ANTIINFLAMMATORY AGENTS ABBOTT LABORATORIES (US) 1996-01-23 US disclosed
WO-1995016687-A1 PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES ABBOTT LABORATORIES (US) 1995-06-22 WO disclosed
EP-0620215-A1 1H-indole-3-acetamide derivatives as sPLA2 inhibitors ELI LILLY AND COMPANY (US) 1994-10-19 EP disclosed