Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 3/20 | 0.42 |
| ▸ | ADH1A | P07327 | 3/20 | 0.42 |
| ▸ | ADH7 | P40394 | 3/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313460 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL14390475 | 0.98 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9313454 | 0.95 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1086964 | 0.87 | THRB (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554413 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22023212 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554404 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554429 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554400 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554406 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4148040-B1 | ONE POT SYNTHESIS OF UREA (METH)ACRYLATES | EVONIK OPERATIONS GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |