Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADH1B | P00325 | 3/20 | 0.37 |
| ▸ | ADH1A | P07327 | 3/20 | 0.37 |
| ▸ | ADH7 | P40394 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132490 | 0.91 | THRB (0.58) | THRBTSHRALDH1A1ADH1BADH1A | |
| SCHEMBL14390475 | 0.89 | TSHR (0.58) | THRBTSHRALDH1A1ADH1BADH1A | |
| SCHEMBL9313454 | 0.89 | TSHR (0.53) | THRBTSHRALDH1A1ADH1BADH1A | |
| SCHEMBL9313460 | 0.87 | TSHR (0.61) | THRBTSHRALDH1A1ADH1BADH1A | |
| SCHEMBL26662014 | 0.87 | TSHR (0.61) | THRBTSHRALDH1A1ADH1BADH1A | |
| SCHEMBL5831740 | 0.85 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9321905 | 0.84 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13950019 | 0.82 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16378672 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5652323 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005055959-A2 | BULKY MONOMERS LEADING TO RESINS EXHIBITING LOW POLYMERIZATION SHRINKAGE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | claimed |
| US-20050124721-A1 | Bulky monomers leading to resins exhibiting low polymerization shrinkage | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-06-09 | — | — | US | claimed |
| US-20040157140-A1 | Photosensitive coloring composition, color filter using the composition and method of producing the same | SHOWA DENKO K.K. (JP) | 2004-08-12 | — | — | US | claimed |
| EP-0358774-B1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES (JP) | 1995-10-25 | — | — | EP | claimed |
| EP-0197635-B1 | ACRYLIC EMULSION COPOLYMERS FOR THICKENING AQUEOUS SYSTEMS AND COPOLYMERIZABLE SURFACTANT MONOMERS FOR USE THEREIN | National Starch and Chemical Investment Holding Corporation (US) | 1991-11-13 | — | — | EP | claimed |
| US-RE33008-E | Acrylic emulsion copolymers for thickening aqueous systems and copolymerizable surfactant monomers for use therein | ALCO CHEMICAL CORPORATION (US) | 1989-08-01 | — | — | US | claimed |
| US-4818801-A | IMPROVED OXYGEN PERMEABILITY; CONTACT LENSES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-04-04 | — | — | US | claimed |
| US-4743698-A | UNSATURATED ISOCYANATE-POLYHYDRIC ALCOHOL (OR PRIMARY AMINE) NONIONIC SURFACTANT REACTION PRODUCTS | ALCO CHEMICAL CORP. (US) | 1988-05-10 | — | — | US | claimed |
| EP-0197635-A2 | Acrylic emulsion copolymers for thickening aqueous systems and copolymerizable surfactant monomers for use therein | National Starch and Chemical Investment Holding Corporation (US) | 1986-10-15 | — | — | EP | claimed |
| US-4600761-A | DISARMING A BOMB;SAFETY DEVICE | ALCO CHEMICAL CORPORATION (US) | 1986-07-15 | — | — | US | claimed |
| EP-2608767-B1 | POLYMER COMPOSITIONS AND METHODS | SAUDI ARAMCO TECH CO (SA) | 2023-07-26 | — | — | EP | disclosed |
| US-11649195-B2 | Smart release nitrogen-containing fertilizer granules | Rynan Technologies Pte Ltd. (SG) | 2023-05-16 | — | — | US | disclosed |
| WO-2022158555-A1 | THERMOSETTING LIQUID CRYSTAL COMPOSITION HAVING PHOTO-ALIGNING CHARACTERISTICS, RETARDATION FILM ALSO SERVING AS ALIGNMENT MEMBRANE AND METHOD FOR MANUFACTURING SAME, RETARDATION PLATE AND METHOD FOR MANUFACTURING SAME, OPTICAL MEMBER AND METHOD FOR MANUFACTURING SAME, AND DISPLAY DEVICE | 大日本印刷株式会社 | 2022-07-28 | — | — | WO | disclosed |
| US-20220220308-A1 | POLYAMIDE-IMIDE BLOCK COPOLYMERS, PREPARATION METHOD THEREOF AND POLYAMIDE-IMIDE FILM COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2022-07-14 | — | — | US | disclosed |
| US-11198751-B2 | Silicone hydrogel contact lenses and method for manufacturing the same | PEGAVISION CORPORATION (TW) | 2021-12-14 | — | — | US | disclosed |
| US-4543398-A | Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| EP-0137634-A2 | Curable epoxy compositions and cured resins obtained therefrom | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-17 | — | — | EP | disclosed |
| EP-0127321-A1 | Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4440918-A | OXYGEN PERMEABILITY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0084406-A1 | Ophthalmic device comprising a polymer of a telechelic perfluoropolyether | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124721-A1 | Bulky monomers leading to resins exhibiting low polymerization shrinkage | REV1, TERB1, RAD51 | THRB 4766/4885TSHR 4811/4885ALDH1A1 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.