Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666270 | 0.87 | KMO (0.47) | KMODYRK1ACLK4GRM2ABL1 | |
| SCHEMBL2666251 | 0.85 | NPC1 (0.49) | KMOCLK4GRM5 | |
| SCHEMBL2666284 | 0.83 | MEN1 (0.40) | KMODYRK1ACLK4CYP1A2KCNH2 | |
| SCHEMBL22578238 | 0.81 | CYP1A2 (0.47) | KMODYRK1ACLK4CYP1A2 | |
| SCHEMBL22130225 | 0.81 | KIT (0.41) | KMO | |
| SCHEMBL31533414 | 0.81 | CYP17A1 (0.46) | — | |
| SCHEMBL2666240 | 0.80 | NOTUM (0.50) | GRM2KDM4CCYP1A2 | |
| SCHEMBL20597708 | 0.77 | KMO (0.44) | KMODYRK1ACLK4GRM2KDM4C | |
| SCHEMBL8226435 | 0.77 | RXRA (0.44) | DYRK1ACLK4CYP1A2 | |
| SCHEMBL12021925 | 0.77 | MEN1 (0.34) | KMODYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728227-B1 | ORGANIC MOLECULES WITH A PYRIDINE-PHENYL CORE FOR USE IN OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO LTD (KR) | 2023-08-16 | — | — | EP | disclosed |
| EP-3728227-A1 | ORGANIC MOLECULES WITH A PYRIDINE-PHENYL CORE FOR USE IN OPTOELECTRONIC DEVICES | cynora GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| WO-2002076983-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-03 | — | — | WO | disclosed |