Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 16/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187280 | 0.81 | MEN1 (0.61) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL12864670 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL31494372 | 0.76 | SMN1; SMN2 (0.49) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL25440335 | 0.73 | KDM4E (0.55) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL31186653 | 0.73 | CYP1A1 (0.46) | MEN1KMT2ACLK4CYP1A2CYP3A4 | |
| SCHEMBL15849494 | 0.73 | TGFBR1 (0.62) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL30030511 | 0.73 | KDM4E (0.66) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL10165327 | 0.72 | ALDH1A1 (0.53) | KMT2AKDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL3592778 | 0.72 | MAPT (0.50) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL7614422 | 0.71 | CLK4 (0.49) | MEN1KMT2AKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076983-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-03 | — | — | WO | disclosed |