⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510704 | 0.86 | TRIM24 (0.44) | — | |
| SCHEMBL4569183 | 0.84 | SHBG (0.32) | — | |
| SCHEMBL1539175 | 0.84 | TRIM24 (0.52) | — | |
| SCHEMBL11321611 | 0.83 | ESR2 (0.35) | — | |
| SCHEMBL9234017 | 0.83 | TRIM24 (0.41) | — | |
| SCHEMBL28670982 | 0.83 | TRIM24 (0.41) | — | |
| SCHEMBL4572173 | 0.81 | TLR4 (0.30) | — | |
| SCHEMBL14864461 | 0.81 | ESR2 (0.31) | — | |
| Ethylene SCHEMBL13834831 | 0.80 | TRIM24 (0.39) | — | |
| SCHEMBL918713 | 0.78 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346602-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA INC (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4525987-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225664-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-11-23 | — | — | WO | disclosed |