Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.44 |
| ▸ | ADCY6 | O43306 | 5/20 | 0.44 |
| ▸ | ADCY3 | O60266 | 5/20 | 0.44 |
| ▸ | ADCY9 | O60503 | 5/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.44 |
| ▸ | ADCY8 | P40145 | 5/20 | 0.44 |
| ▸ | ADCY7 | P51828 | 5/20 | 0.44 |
| ▸ | ADCY2 | Q08462 | 5/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.44 |
| ▸ | ADCY4 | Q8NFM4 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755461 | 0.91 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL6755575 | 0.79 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2655411 | 0.79 | GCGR (0.45) | GCGRPOLBGLP1R | |
| SCHEMBL2654576 | 0.79 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2666436 | 0.78 | KMO (0.38) | GCGR | |
| SCHEMBL2652488 | 0.77 | FABP4 (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL6755462 | 0.77 | GCGR (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2655108 | 0.77 | GCGR (0.43) | GCGR | |
| SCHEMBL2653398 | 0.77 | GCGR (0.56) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2659187 | 0.77 | GCGR (0.66) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |