Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | GCG | P01275 | 2/20 | 0.36 |
| ▸ | GIPR | P48546 | 1/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662324 | 0.81 | GCGR (0.51) | GCGRGLP1RALDH1A1POLBGCG | |
| SCHEMBL6917620 | 0.81 | GCGR (0.51) | GCGRGLP1RALDH1A1POLBGCG | |
| SCHEMBL2653302 | 0.81 | ALDH1A1 (0.47) | GCGRGLP1RALDH1A1POLBGCG | |
| SCHEMBL2655272 | 0.80 | ALDH1A1 (0.47) | GCGRGLP1RALDH1A1POLBGPR139 | |
| SCHEMBL2652499 | 0.80 | GCGR (0.49) | GCGRGLP1RALDH1A1POLBGPR139 | |
| SCHEMBL2655274 | 0.80 | GCGR (0.49) | GCGRGLP1RALDH1A1POLBGPR139 | |
| SCHEMBL2666436 | 0.79 | KMO (0.38) | GCGRGIPR | |
| SCHEMBL2660981 | 0.79 | GCGR (0.49) | GCGRGLP1RALDH1A1POLBGCG | |
| SCHEMBL2653905 | 0.78 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2655106 | 0.77 | GCGR (0.47) | GCGRALDH1A1POLBGCGGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |