Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23207693 | 0.86 | LIPE (0.47) | LIPECHRNB2CHRNA4ALOX5APFEN1 | |
| SCHEMBL23207692 | 0.86 | LIPE (0.47) | LIPECHRNB2CHRNA4ALOX5APFEN1 | |
| SCHEMBL21607026 | 0.86 | HRH1 (0.47) | LIPECHRNB2CHRNA4TRPV4AXL | |
| Hydrochloric Acid SCHEMBL29913019 | 0.84 | HRH1 (0.46) | LIPECHRNB2CHRNA4TRPV4AXL | |
| Hydrochloric Acid SCHEMBL23168140 | 0.84 | LIPE (0.46) | LIPECHRNB2CHRNA4ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL27157929 | 0.84 | HRH1 (0.46) | LIPECHRNB2CHRNA4TRPV4AXL | |
| Hydrochloric Acid SCHEMBL23168136 | 0.84 | LIPE (0.46) | LIPECHRNB2CHRNA4ALOX5APFEN1 | |
| SCHEMBL20085932 | 0.83 | PARP10 (0.39) | LIPECHRNB2CHRNA4PARP10ABL1 | |
| SCHEMBL4375065 | 0.82 | LIPE (0.47) | LIPECHRNB2CHRNA4ALOX5APFEN1 | |
| SCHEMBL26709805 | 0.82 | CHRNB2 (0.46) | LIPECHRNB2CHRNA4ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |