Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645225 | 1.00 | DNM1 (0.61) | DNM1MAPTSMN1; SMN2P2RX3KMT2A | |
| SCHEMBL406098 | 0.85 | DNM1 (0.62) | DNM1MAPTSMN1; SMN2P2RX3KMT2A | |
| SCHEMBL21093044 | 0.84 | RAD52 (0.53) | DNM1MAPTSMN1; SMN2KMT2AHTT | |
| SCHEMBL21093026 | 0.84 | RAD52 (0.53) | DNM1MAPTSMN1; SMN2KMT2AHTT | |
| SCHEMBL21093057 | 0.84 | RAD52 (0.53) | DNM1MAPTSMN1; SMN2KMT2AHTT | |
| SCHEMBL21093337 | 0.84 | RAD52 (0.53) | DNM1MAPTSMN1; SMN2KMT2AHTT | |
| SCHEMBL410834 | 0.81 | DNM1 (0.73) | DNM1MAPTSMN1; SMN2P2RX3KMT2A | |
| SCHEMBL16099375 | 0.80 | DNM1 (0.67) | DNM1MAPTSMN1; SMN2P2RX3KMT2A | |
| SCHEMBL21093003 | 0.80 | BACE1 (0.62) | DNM1SMN1; SMN2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL407863 | 0.80 | DNM1 (0.64) | DNM1MAPTSMN1; SMN2P2RX3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225300-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | EMORY UNIVERSITY (US) | 2023-11-23 | — | — | WO | claimed |
| WO-2023225300-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | EMORY UNIVERSITY (US) | 2023-11-23 | — | — | WO | disclosed |