Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SORD | Q00796 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26600738 | 0.88 | HRH4 (0.62) | HRH3HRH4CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL30618987 | 0.88 | HRH4 (0.62) | HRH3HRH4CYP1A2CYP2C9ADRB1 | |
| SCHEMBL9368732 | 0.84 | HRH3 (0.59) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| Hydrochloric Acid SCHEMBL17580670 | 0.83 | HRH3 (0.58) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| Hydrochloric Acid SCHEMBL15106704 | 0.83 | HRH3 (0.58) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| SCHEMBL26611673 | 0.82 | HRH3 (0.54) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| SCHEMBL11919248 | 0.81 | HRH3 (0.59) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| SCHEMBL906132 | 0.80 | HTR1A (0.53) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| Hydrochloric Acid SCHEMBL6978271 | 0.80 | HRH3 (0.58) | HRH3HRH4CYP1A2HSD17B10PLD1 | |
| SCHEMBL26819125 | 0.78 | ACHE (0.44) | HRH3HRH4SORDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | HRH3 4494/4885HRH4 4558/4885CYP1A2 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.