Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669305 | 0.83 | GCK (0.32) | GCKKCNH2 | |
| SCHEMBL2667101 | 0.83 | GCK (0.40) | GCK | |
| SCHEMBL1427026 | 0.72 | CA1 (0.56) | — | |
| SCHEMBL2666697 | 0.71 | TDP1 (0.33) | GCK | |
| SCHEMBL2666549 | 0.69 | GCK (0.38) | GCK | |
| SCHEMBL13209318 | 0.68 | GCK (0.34) | GCKKCNH2 | |
| SCHEMBL13209296 | 0.67 | GCK (0.42) | GCK | |
| SCHEMBL13209323 | 0.67 | GCK (0.42) | GCK | |
| SCHEMBL1427049 | 0.65 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL1426914 | 0.65 | GCK (0.65) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007041-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |