Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.58 |
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835100 | 0.82 | TAAR1 (0.59) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL13067159 | 0.81 | SMN1; SMN2 (0.50) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL15457417 | 0.81 | IDO1 (0.68) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL29034446 | 0.74 | HTT (0.59) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL13067268 | 0.74 | SMN1; SMN2 (0.43) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL66777 | 0.74 | SMN1; SMN2 (0.50) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL29620133 | 0.74 | SMN1; SMN2 (0.50) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL13689952 | 0.74 | PKM (0.53) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL12835039 | 0.73 | IDO1 (0.68) | TAAR1IDO1SMN1; SMN2LMNAHTT | |
| SCHEMBL13007579 | 0.73 | IDO1 (1.00) | TAAR1IDO1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117381-A9 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007117381-A2 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2007-10-18 | — | — | WO | disclosed |