Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067268 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL2667321 | 0.81 | TAAR1 (0.58) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL13067317 | 0.80 | LMNA (0.30) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL12835100 | 0.75 | TAAR1 (0.59) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL15457417 | 0.74 | IDO1 (0.68) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL29034446 | 0.68 | HTT (0.59) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL13689952 | 0.67 | PKM (0.53) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL12835039 | 0.67 | IDO1 (0.68) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL13007579 | 0.67 | IDO1 (1.00) | SMN1; SMN2TAAR1IDO1HTTLMNA | |
| SCHEMBL27592486 | 0.67 | LMNA (0.68) | SMN1; SMN2TAAR1IDO1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132999-A1 | METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | CHLORION PHARMA, INC. (CA) | 2010-11-25 | — | — | WO | disclosed |