Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GCK | P35557 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667759 | 0.89 | GCK (0.47) | F2F10GCK | |
| SCHEMBL9070932 | 0.87 | GCK (0.44) | ALDH1A1SMN1; SMN2F2F10GCK | |
| SCHEMBL9070832 | 0.85 | F10 (0.43) | ALDH1A1SMN1; SMN2LMNAF2F10 | |
| SCHEMBL2667444 | 0.85 | F2 (0.41) | F2F10GCK | |
| SCHEMBL2667770 | 0.84 | F2 (0.43) | ALDH1A1SMN1; SMN2LMNAF2F10 | |
| SCHEMBL2667727 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2LMNAHTT | |
| SCHEMBL2667771 | 0.81 | SCN9A (0.43) | ALDH1A1LMNAF2F10GAA | |
| SCHEMBL2667377 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2LMNAHTT | |
| SCHEMBL2667379 | 0.79 | GCK (0.57) | GCK | |
| SCHEMBL9071042 | 0.79 | GCK (0.62) | ALDH1A1TSHRSMN1; SMN2LMNAGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |