Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | GCK | P35557 | 3/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667770 | 0.87 | F2 (0.43) | F10ALDH1A1SMN1; SMN2F2GCK | |
| SCHEMBL2667976 | 0.87 | F10 (0.37) | F10F2GCKBRD4 | |
| SCHEMBL2667376 | 0.85 | ALDH1A1 (0.42) | F10ALDH1A1SMN1; SMN2F2GCK | |
| SCHEMBL2667759 | 0.83 | GCK (0.47) | F10F2GCK | |
| SCHEMBL2667771 | 0.83 | SCN9A (0.43) | F10ALDH1A1F2ST14PRSS1 | |
| SCHEMBL2667997 | 0.82 | GCK (0.49) | F10HPGDF2GCKST14 | |
| SCHEMBL2667693 | 0.82 | GCK (0.47) | F10HPGDF2GCKST14 | |
| SCHEMBL9070932 | 0.82 | GCK (0.44) | F10ALDH1A1SMN1; SMN2F2GCK | |
| SCHEMBL9071052 | 0.81 | F2 (0.41) | F10ALDH1A1SMN1; SMN2F2GCK | |
| SCHEMBL2667561 | 0.80 | F10 (0.51) | F10ALDH1A1SMN1; SMN2F2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |