Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GCK | P35557 | 6/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667366 | 0.98 | TDP1 (0.66) | TDP1GCKUSP2ALDH1A1LMNA | |
| SCHEMBL2667525 | 0.94 | GCK (0.58) | TDP1GCKUSP2ALDH1A1LMNA | |
| SCHEMBL2667389 | 0.89 | ALDH1A1 (0.56) | TDP1GCKUSP2ALDH1A1LMNA | |
| SCHEMBL2668002 | 0.87 | ALDH1A1 (0.58) | TDP1GCKUSP2ALDH1A1LMNA | |
| SCHEMBL2667385 | 0.87 | ALDH1A1 (0.69) | TDP1GCKALDH1A1LMNAMAPK1 | |
| SCHEMBL2667679 | 0.87 | GCK (0.78) | GCKALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL2667384 | 0.87 | TSHR (0.59) | GCKUSP2ALDH1A1LMNAMAPK1 | |
| SCHEMBL2667369 | 0.85 | ALDH1A1 (0.72) | TDP1ALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL2667364 | 0.85 | TSHR (0.62) | GCKUSP2ALDH1A1LMNAMAPK1 | |
| SCHEMBL2667529 | 0.83 | ALDH1A1 (0.51) | TDP1GCKUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |