Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667675 | 0.88 | GCK (0.52) | GCK | |
| SCHEMBL9071040 | 0.86 | GCK (0.48) | GCK | |
| SCHEMBL2667377 | 0.85 | ALDH1A1 (0.44) | GCK | |
| SCHEMBL9070933 | 0.84 | GCK (0.58) | GCK | |
| SCHEMBL2667365 | 0.84 | GCK (0.49) | GCKPTGDR | |
| SCHEMBL2667775 | 0.84 | CCNA2 (0.45) | GCKCCNA2CDK2CCNA1 | |
| SCHEMBL9070995 | 0.83 | GCK (0.40) | GCK | |
| SCHEMBL2667654 | 0.81 | GCK (0.47) | GCKCCNA2CDK2CCNA1 | |
| SCHEMBL9070927 | 0.81 | SMN1; SMN2 (0.42) | GCK | |
| SCHEMBL2667444 | 0.81 | F2 (0.41) | GCKPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |