Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26675757 | 1.00 | GAA (0.56) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL30716719 | 1.00 | GAA (0.56) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL26675782 | 1.00 | GAA (0.56) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL4716210 | 0.87 | GAA (0.55) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL4716206 | 0.87 | GAA (0.55) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL2793284 | 0.84 | GAA (0.58) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL2789965 | 0.82 | MAPT (0.55) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL2789608 | 0.82 | LMNA (0.59) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL21464112 | 0.81 | GAA (0.57) | GAACYP1A2HDAC8SMN1; SMN2MAPT | |
| SCHEMBL1473102 | 0.81 | LMNA (0.58) | GAACYP1A2HDAC8SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382909-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382909-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | GAA 172/4885CYP1A2 107/4885HDAC8 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.