Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667687 | 0.99 | GCK (0.51) | GCKL3MBTL1KCNH2RARARARB | |
| SCHEMBL9071013 | 0.94 | GCK (0.49) | GCKL3MBTL1KCNH2RARARARB | |
| SCHEMBL2667993 | 0.93 | L3MBTL1 (0.47) | GCKL3MBTL1KCNH2 | |
| SCHEMBL2667368 | 0.91 | GCK (0.48) | GCKL3MBTL1KCNH2 | |
| SCHEMBL2667582 | 0.90 | L3MBTL1 (0.58) | GCKL3MBTL1KCNH2RARG | |
| SCHEMBL2667644 | 0.89 | GCK (0.64) | GCKKCNH2RARARARBRARG | |
| SCHEMBL2667688 | 0.88 | GCK (0.63) | GCKKCNH2RARARARBRARG | |
| SCHEMBL2667570 | 0.88 | GCK (0.54) | GCKRARARARBRARG | |
| SCHEMBL2667972 | 0.88 | GCK (0.59) | GCKKCNH2RARARARBRARG | |
| SCHEMBL9070852 | 0.87 | GCK (0.52) | GCKRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |