Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667993 | 0.98 | L3MBTL1 (0.47) | GCKKCNH2L3MBTL1RXFP1KMT2A | |
| SCHEMBL9070837 | 0.94 | GCK (0.43) | GCKKCNH2L3MBTL1ALDH1A1PTGDR | |
| SCHEMBL2667732 | 0.93 | GCK (0.46) | GCKKCNH2KMT2AALDH1A1GAA | |
| SCHEMBL2667687 | 0.93 | GCK (0.51) | GCKKCNH2L3MBTL1 | |
| SCHEMBL2667579 | 0.91 | GCK (0.51) | GCKKCNH2L3MBTL1 | |
| SCHEMBL2667442 | 0.88 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL2667363 | 0.87 | GCK (0.54) | GCKKCNH2L3MBTL1 | |
| SCHEMBL9071038 | 0.87 | GCK (0.48) | GCK | |
| SCHEMBL9070835 | 0.87 | GCK (0.52) | GCKKCNH2 | |
| SCHEMBL9071013 | 0.86 | GCK (0.49) | GCKKCNH2L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |