Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.51 |
| ▸ | PDE5A | O76074 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667704 | 1.00 | SCD (0.51) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667668 | 0.87 | ALDH1A1 (0.52) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667629 | 0.87 | ALDH1A1 (0.52) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667614 | 0.87 | ALDH1A1 (0.52) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667590 | 0.86 | MAPK1 (0.47) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667724 | 0.84 | KDM4E (0.50) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2668009 | 0.83 | GRM5 (0.48) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667666 | 0.83 | SCD (0.48) | SCDPDE5AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2667764 | 0.83 | RAB9A (0.49) | PDE5AKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL2667555 | 0.82 | GCK (0.53) | SCDPDE5AKDM4EALDH1A1PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |