Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | AQP4 | P55087 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070874 | 0.84 | RAB9A (0.59) | RAB9ALMNAKDM4EAQP4KMT2A | |
| SCHEMBL2667663 | 0.84 | GCK (0.53) | RAB9AKDM4EPDE4BKMT2AMEN1 | |
| SCHEMBL2667662 | 0.84 | GRM5 (0.59) | RAB9AGRM5KMT2AMEN1NPC1 | |
| SCHEMBL2667595 | 0.81 | MAPK1 (0.45) | RAB9ALMNAKDM4EGRM5NPC1 | |
| SCHEMBL2667596 | 0.80 | RAB9A (0.49) | RAB9ALMNAKDM4EMAPK14AQP4 | |
| SCHEMBL9070881 | 0.79 | RAB9A (0.51) | RAB9ALMNAKDM4EGRM5AQP4 | |
| SCHEMBL9070878 | 0.79 | RAB9A (0.51) | RAB9ALMNAKDM4EGRM5AQP4 | |
| SCHEMBL9070877 | 0.79 | RAB9A (0.51) | RAB9ALMNAKDM4EGRM5AQP4 | |
| SCHEMBL9070805 | 0.79 | RAB9A (0.50) | RAB9ALMNAKDM4EAQP4KMT2A | |
| SCHEMBL9070820 | 0.78 | RAB9A (0.49) | RAB9ALMNAKDM4EAQP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |