Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | CPT1A | P50416 | 4/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667593 | 0.90 | MAPK1 (0.60) | MAPK1HTTALDH1A1TDP1LMNA | |
| SCHEMBL2667662 | 0.86 | GRM5 (0.59) | GRM5ALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL2667590 | 0.82 | MAPK1 (0.47) | MAPK1HTTPDE5AALDH1A1LMNA | |
| SCHEMBL2668009 | 0.82 | GRM5 (0.48) | MAPK1HTTPDE5AGRM5ALDH1A1 | |
| SCHEMBL2667587 | 0.81 | SCD (0.51) | MAPK1HTTPDE5AALDH1A1SCD | |
| SCHEMBL2667704 | 0.81 | SCD (0.51) | MAPK1HTTPDE5AALDH1A1SCD | |
| SCHEMBL2667663 | 0.81 | GCK (0.53) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2667599 | 0.81 | RAB9A (0.47) | GRM5ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2667629 | 0.80 | ALDH1A1 (0.52) | MAPK1HTTPDE5AALDH1A1SCD | |
| SCHEMBL2667668 | 0.80 | ALDH1A1 (0.52) | MAPK1HTTPDE5AALDH1A1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |