Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 6/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | CCND3 | P30281 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667482 | 0.99 | CCNE2 (0.44) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL9071847 | 0.94 | CCNE2 (0.47) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL9072844 | 0.81 | CCNE1 (0.62) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL2667689 | 0.80 | CCNE1 (0.46) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL2666139 | 0.79 | RAB9A (0.50) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL12384824 | 0.78 | CCNE1 (0.41) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL2656567 | 0.77 | CDK2 (0.42) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL2656562 | 0.77 | CDK2 (0.42) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL12384837 | 0.76 | CDK2 (0.42) | CDK2CCNE2CCNE1CCNB2CDK1 | |
| SCHEMBL1240423 | 0.76 | CDK2 (0.44) | CDK2CCNE2CCNE1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006761-A1 | DICYCLOALKYLCARBAMOYL UREAS AS GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |