Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26677157 | 1.00 | PARP15 (0.46) | PARP15PARP10ACACBPDE4BPDE4A | |
| SCHEMBL1853454 | 0.80 | PARP10 (0.41) | PARP15PARP10ACACBPARP2 | |
| SCHEMBL2548460 | 0.77 | LMNA (0.43) | HSD17B10 | |
| SCHEMBL26655457 | 0.77 | PARP15 (0.50) | PARP15PARP10ACACBPDE4BPDE4A | |
| SCHEMBL26655461 | 0.77 | PARP15 (0.50) | PARP15PARP10ACACBPDE4BPDE4A | |
| SCHEMBL26796630 | 0.74 | PARP15 (0.46) | PARP15PARP10ACACBPDE4BPDE4A | |
| SCHEMBL30636047 | 0.74 | PARP15 (0.46) | PARP15PARP10ACACBPDE4BPDE4A | |
| SCHEMBL5655847 | 0.74 | PTGDR2 (0.38) | HSD17B10 | |
| SCHEMBL8901981 | 0.71 | PARP10 (0.68) | PARP15PARP10ACACBPDE4BPDE4A | |
| SCHEMBL3225566 | 0.68 | DRD2 (0.40) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276097-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2023-11-15 | — | — | EP | disclosed |