SCHEMBL26677486

SCHEMBL26677486

C[Si](C)(C)CCOCn1nc(Br)c(Br)n1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26849367 0.82 DGAT1 (0.32) DGAT1
SCHEMBL31469360 0.81 DGAT1 (0.36) DGAT1
SCHEMBL26677622 0.81 DGAT1 (0.32) DGAT1
SCHEMBL24828271 0.80 DGAT1 (0.33) DGAT1
SCHEMBL26101590 0.80 DGAT1 (0.45) DGAT1
SCHEMBL23294574 0.80 NPSR1 (0.33) DGAT1
SCHEMBL31419057 0.78 DGAT1 (0.35) DGAT1
SCHEMBL23294459 0.78 TARBP2 (0.40)
SCHEMBL21259853 0.77 DGAT1 (0.42) DGAT1
SCHEMBL15702149 0.74 DGAT1 (0.36) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720064-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2026-04-08 EP disclosed
EP-4532485-A1 TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2025-04-09 EP disclosed
WO-2024246602-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2024-12-05 WO disclosed
WO-2023227946-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2023-11-30 WO disclosed