Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.32 |
| ▸ | FEN1 | P39748 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | CASP1 | P29466 | 4/20 | 0.31 |
| ▸ | CASP7 | P55210 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101590 | 0.87 | DGAT1 (0.45) | DGAT1ALOX5APFEN1HSD17B10ALDH1A1 | |
| SCHEMBL9948523 | 0.83 | ERBB2 (0.37) | DGAT1F11NPC1MEN1KMT2A | |
| SCHEMBL26677486 | 0.81 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL26453168 | 0.78 | DGAT1 (0.37) | DGAT1F11NPC1MEN1KMT2A | |
| SCHEMBL4839289 | 0.78 | F11 (0.39) | DGAT1F11NPC1MAPK1KDM4E | |
| SCHEMBL31469232 | 0.76 | LIPG (0.40) | DGAT1F11KEAP1NFE2L2 | |
| SCHEMBL31469288 | 0.75 | DGAT1 (0.42) | DGAT1F11NPC1 | |
| SCHEMBL26979580 | 0.74 | DGAT1 (0.39) | DGAT1NR1H2NR1H3NPC1KDM4E | |
| SCHEMBL13510721 | 0.73 | NR1H3 (0.44) | NR1H2NR1H3NPC1MEN1KMT2A | |
| SCHEMBL25120641 | 0.72 | NR1H3 (0.46) | DGAT1NR1H2NR1H3NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |