Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26689195 | 0.98 | ALDH1A1 (0.39) | ALDH1A1NOTUMPKMPDE2AKDM4E | |
| SCHEMBL30686749 | 0.98 | ALDH1A1 (0.39) | ALDH1A1NOTUMPKMPDE2AKDM4E | |
| Bicarbonate SCHEMBL26677805 | 0.91 | NOTUM (0.43) | ALDH1A1NOTUMPDE2AKDM4ESMN1; SMN2 | |
| SCHEMBL15893966 | 0.73 | CNR2 (0.47) | ALDH1A1NOTUMHTR2BHTR2AHTR2C | |
| SCHEMBL22843391 | 0.71 | NOTUM (0.50) | ALDH1A1NOTUMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL12356967 | 0.71 | CNR2 (0.42) | ALDH1A1NOTUMHTR2BHTR2AHTR2C | |
| SCHEMBL23366510 | 0.71 | KDM4E (0.35) | ALDH1A1PKMKDM4EHSD17B3MEN1 | |
| SCHEMBL16525749 | 0.68 | HPGD (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL17359363 | 0.67 | CYBB (0.39) | ALDH1A1NOTUMPKMPDE2AKDM4E | |
| SCHEMBL19088585 | 0.63 | MAPT (0.46) | ALDH1A1PDE2AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381812-A1 | Method of Selective Deposition of Small Molecules on Metal Surfaces | UNIVERSITE LAVAL (CA) | 2023-11-30 | — | — | US | disclosed |
| WO-2023201437-A1 | METHOD OF SELECTIVE DEPOSITION OF SMALL MOLECULES ON METAL SURFACES | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-10-26 | — | — | WO | disclosed |