Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109275 | 0.82 | MEN1 (0.42) | ATMKDM4EKMOPTGDR2 | |
| SCHEMBL19302753 | 0.78 | KDM4E (0.55) | APEX1KDM4E | |
| SCHEMBL30637086 | 0.77 | ATM (0.76) | APEX1ATMKDM4EMAOB | |
| SCHEMBL30637088 | 0.76 | APEX1 (0.54) | APEX1ATMKDM4EMAOB | |
| SCHEMBL26679499 | 0.76 | APEX1 (0.54) | APEX1ATMKDM4EMAOB | |
| SCHEMBL23013887 | 0.75 | CYP2C19 (0.41) | — | |
| SCHEMBL30637114 | 0.75 | APEX1 (0.49) | APEX1ATMKDM4EMAOB | |
| SCHEMBL10779339 | 0.74 | KDM4E (0.70) | KDM4EFFAR1 | |
| SCHEMBL31711209 | 0.72 | APEX1 (0.49) | APEX1ATMKDM4EMAOB | |
| SCHEMBL30637106 | 0.72 | APEX1 (0.49) | APEX1ATMKDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522595-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | The Scripps Research Institute (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220559-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220559-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-16 | — | — | WO | disclosed |